Clinical Research

Clinical Trials

Clinical trials are investigations where patients willingly participate to contribute to the discovery of answers to health inquiries. When conducted with caution, they represent the most secure and efficient method of uncovering novel treatments and enhancing overall well-being. The advancement of medicine would not be possible without the continued participation of patients in clinical research.

Samaritan’s clinical research program was established in 2008. Sponsors have included: Pfizer, Boehringer Ingelheim, Spectrum, Celgene, Genentech, Amgen, Genentech, Tragara, Bracco Diagnostic, Eisai, PUMA, Novartis, Incyte, Pharmatech, Medtronic, St. Jude Medical and the National Institutes of Health.

• National Institute of Health and Federal Drug Administration registration number: IRB00005278.
• Institutional Organization Number (IORG) is IORG0004448.
• We are a research affiliate of UCSF for The Alliance for Clinical Trials in Oncology.

For more information, email clinicalresearch@samhealth.org or call 541-768-4352.

Current Studies

Infectious Disease

Title	More Information
TitleBlood Purification for the Treatment of Pathogen Associated Shock (PURIFY-RCT) Principal Investigator: Brian Delmonaco, MD	For more information on this trial.
TitleAssessment of Implementation Methods in Sepsis and Respiratory Failure (AIMS) Principal Investigator: Brian Delmonaco, MD	Email clinicalresearch@samhealth.org
TitleCOVID-19 Specimen Biobank Principal Investigator: Adam Brady, MD	Email clinicalresearch@samhealth.org

Cancer

Breast

Title	More Information
TitleMaking Informed Choices on Incorporating Chemoprevention Into Care (MiCHOICE) Principal Investigator: Rachel Shirley, DO	For more information on this trial.
TitleA Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer (EMBER-4) Principal Investigator: Robert Davis, MD	For more information on this trial.

Lung

Title	More Information
Lung Cancer Screening Program Principal Investigator: Vanessa Mizak, NP, and Brian Delmonaco, MD	Email: clinicalresearch@samhealth.org
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial) Principal Investigator: John Strother, MD	For more information on this trial.
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, ALCHEMIST Chemo-IO Study Principal Investigator: John Strother, MD	For more information on this trial.
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial) Principal Investigator: John Strother, MD	For more information on this trial.
Lung Cancer Companion Diagnostic  Principal Investigator: Tomer Pelleg, DO	Email clinicalresearch@samhealth.org

Other

Title	More Information
Multiple Metastatic Tumors Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas or Multiple Myeloma (The MATCH Screening Trial) Principal Investigator: John Strother, MD	For more information on this trial.
Sarcoma Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds Principal Investigator: Nicholas Tedesco, DO	For more information on this trial.
Orthopedic Tumor Surgery Orthopedic Tumor Data Registry Principal Investigator: Nicholas Tedesco, DO	Email: clinicalresearch@samhealth.org
realMIND: Observational Study of Patients With Relapsed or Refractory DLBCL Starting Second- or Third-line Therapy (realMIND) Principal Investigator: Robert Davis, MD	For more information on this trial.
Metastatic Bone Reconstructions Principal Investigator: Nicholas Tedesco, DO	Email: clinicalresearch@samhealth.org
Multiple Solid Tumor Cancer Detection   Principal Investigator: John Strother, MD	Email: clinicalresearch@samhealth.org
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors Principal Investigator: John Strother, MD	For more information on this trial.

Cardiology

Title	More Information
TitleStudy of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease (VICTORION-2P) Principal Investigator: Jeremy Warner, DO	For more information on this trial.

Rheumatology

Title	More Information
TitleA Study of Baricitinib in Participants With Rheumatoid Arthritis (RA-BRANCH) Principal Investigator: Jonathan Jones, MD	For more information on this trial.
TitleCorrona Rheumatoid Arthritis (RA) Drug Safety & Effectiveness Registry Principal Investigator: Jonathan Jones, MD	For more information on this trial.
TitleRheumatology Biorepository Principal Investigator: Jonathan Jones, MD	For more information on this trial.
TitleA Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs Principal Investigator: Jonathan Jones, MD	For more information on this trial.

Other

Title	More Information
TitleBenign Soft Tissue Tumor Resection Principal Investigators: Jared Sanderford, DO, and Nicholas Tedesco, DO	Email: clinicalresearch@samhealth.org
TitleUse of Empagliflozin to Treat Prediabetes – a Randomized, Double-blind, Placebo-controlled 13-week Intervention Trial Principal Investigators: Sean Newsom, PhD, and Matthew Robinson, Ph.D. (Oregon State University)	For more information on this trial.
TitleA survey study on the effects of Purewick external catheterizing during hospitalization on urinary incontinence in adults.  Principal Investigators: Breanne Myers, PT, DPT, and Stacy Mosbrucker, PTA, BS	Email: shsresearch@samhealth.org
TitleResponses to Life Stresses Survey Principal Investigator: Thomas Field, Ph.D. (Oregon State University)	Email: shsresearch@samhealth.org