Clinical Research

Clinical Trials

Clinical trials are investigations where patients willingly participate to contribute to the discovery of answers to health inquiries. When conducted with caution, they represent the most secure and efficient method of uncovering novel treatments and enhancing overall well-being. The advancement of medicine would not be possible without the continued participation of patients in clinical research.

Samaritan’s clinical research program was established in 2008. Sponsors have included: Pfizer, Boehringer Ingelheim, Spectrum, Celgene, Genentech, Amgen, Genentech, Tragara, Bracco Diagnostic, Eisai, PUMA, Novartis, Incyte, Pharmatech, Medtronic, St. Jude Medical and the National Institutes of Health.

  • National Institute of Health and Federal Drug Administration registration number: IRB00005278.
  • Institutional Organization Number (IORG) is IORG0004448.
  • We are a research affiliate of UCSF for The Alliance for Clinical Trials in Oncology.

For more information, email [email protected] or call 541-768-4352.

Current Studies

Sepsis & Acute Kidney Injury

TitleMore Information
Assessment of Implementation Methods in Sepsis and Respiratory Failure (AIMS)
Principal Investigator: Brian Delmonaco, MD
Email [email protected].
Placebo-controlled Study to Evaluate the Efficacy and Safety of Tozorakimab (MEDI3506) in Patients Hospitalized for Viral Lung Infection Requiring Supplemental Oxygen
Principal Investigator: Brian Delmonaco, MD
For more information on this trial.
Pivotal Study to Assess the Safety and Efficacy of a Selective Cytopheretic Device in Patients with Acute Kidney Injury Requiring Continuous Kidney Replacement Therapy
Principal Investigator: Brian Delmonaco, MD
For more information on this trial.
Study to Investigate the Safety and Efficacy of TIN816 Via a Single Intravenous Infusion in the Treatment of Participants with Sepsis-associated Acute Kidney Injury (SA-AKI)
Principal Investigator: Brian Delmonaco, MD
For more information on this trial.

Breast

TitleMore Information
Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician’s Choice in Patients with Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy
Principal Investigator:  John Strother, MD
For more information on this trial.
A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer (EMBER-4)
Principal Investigator: Robert Davis, MD
For more information on this trial.

Lung

TitleMore Information
Study of MK-2870 in Combination with Pembrolizumab Compared to Pembrolizumab Monotherapy in the First-line Treatment of Participants with Metastatic Non-small Cell Lung Cancer With PD-L1 TPS Greater Than or Equal to 50% (TroFuse-007)
Principal Investigator: John Strother, MD
For more information on this trial.
Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants with Resected Stage II, IIIA, IIIB (N2) Non-small Cell Lung Cancer (INTerpath-002)
Principal Investigator: John Strother, MD
For more information on this trial.
Nightingale Study – Clinical Utility of Management of Patients with CT and LDCT Identified Pulmonary Nodules Using the Percepta Nasal Swab Classifier – with Familiarization
Principal Investigator: Tomer Pelleg, DO
For more information on this trial.

Other

TitleMore Information
Orthopedic Tumor Surgery
Orthopedic Tumor Data Registry

Principal Investigator: Nicholas Tedesco, DO
Email: [email protected].
Multiple Solid Tumor Cancer Detection  
Principal Investigator: John Strother, MD
Email: [email protected].
Metastatic Bone reconstruction – Serum Cobalt
Principal Investigators:
Taylor Harris, DO & Nicholas Tedesco, DO
Email [email protected].

TitleMore Information
Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults with Elevated Lipoprotein(a) Who Have Established Atherosclerotic Cardiovascular Disease or Are at Risk for a First Cardiovascular Event – ACCLAIM-Lp(a)
Principal Investigator: Jeremy Warner, DO
For more information on this trial.

TitleMore Information
Corrona Rheumatoid Arthritis (RA) Drug Safety & Effectiveness Registry
Principal Investigator: Jonathan Jones, MD
For more information on this trial.
Rheumatology Biorepository
Principal Investigator: Jonathan Jones, MD
For more information on this trial.
Placebo-Controlled Multicenter Trial with Open-Label Extension to Evaluate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 Subcutaneous Administered by Prefilled Syringe in Adult Patients with Primary Sjögren’s Disease
Principal Investigator: Jonathan Jones, MD
For more information on this trial.

TitleMore Information
Benign Soft Tissue Tumor Resection
Principal Investigators: Jared Sanderford, DO, and Nicholas Tedesco, DO
Email: [email protected].
A Prospective Multi-site Registry of Real-world Experience With the Optilume™ BPH Catheter System for Treatment of Men experiencing Symptomatic BPH
Principal Investigator: Eric Martin, MD
For more information on this trial.

Contact Us

For more information about clinical research at Samaritan, please call 541-768-4352 or email us at [email protected].

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